Area Engineer - Small Molecule Building - Lilly Medicine Foundry

Eli Lilly

Lebanon, IN

Pay: $67,500-$173,800/yr

Shift: Full time

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first-ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

The Area Engineer is the site Subject Matter Expert (SME) for the Small Molecules (SM) building and the associated ancillary systems within the FUME (Facilities, Utilities Maintenance & Engineering) organization. During the project phase, the Area Engineer will be a key player in the cross functional project team in assisting in the design, construction, commissioning, qualification, start-up and operational readiness of all systems associated within the Lilly Medicine Foundry’s SM building. During the day-to-day operation, the Area Engineer will be responsible for effectively, reliably, and cost consciously overseeing and maintaining the site’s SM building and associated ancillary systems.

This includes maintaining all systems in a state of compliance, in-control, and fit for use in order to meet the needs of internal customers and/or the business. The Area Engineer will also be responsible for driving continuous improvement initiatives and managing both annual operating expenses and local capital investments for either requested revisions and/or new functionality or capacity. The Area Engineer will also act as the single point of contact for all residents / customers associated with the SM building.

**Responsibilities:**

• Be the SME with a deep technical expertise in all systems under his/her responsibility, understanding their applications in pharmaceutical manufacturing, understanding flow charts and process parameters, and awareness of industry trends including but not limited to the following building systems:

•

• API Reactor Suite(s)
• Fixed reactors and condensers (50 – 500 gallons)
• Agitated Filter Dryers (AFD)
• Temperature Control Units (TCU’s)
• Solvent Filtering and Distribution
• High Potency API Production
• Level III containment
• ISO 8 environment
• Isolators and portable tanks
• Experimental Materials Lab (EML)
• Downflow booths
• Walk-In / bench top fume hoods
• Purified Water w/ Endotoxin Control (PWEC)
• Bulk solvent distribution within the SM building
• Gray / clean utility distribution within the SM building
• Primary and Secondary waste streams within the SM building
• Ensure the assigned processes are aligned with Industry and Lilly Standards
• Support risk assessment exercises using the different tools available (e.g. FMEA)
• Participate as required in teams, committees, or other groups and/or individually to achieve FUME’s departmental, site and/or company goals.

Initial project asset delivery phase and future local capital investment:

• Lead or participate in projects/changes for all the systems under his/her responsibility in the SM building including design, verification activities (IV/OV/PQ), as user representative for capital projects or delivery agent for local projects.
• Develop the proper documentation (URS (User Requirement Specifications), test cases, etc..) to demonstrate that systems are properly installed, qualified and started up and remain in a state of control.
• Contribute to the process resource assessment, capital plans, expense budgets, and prioritize as appropriate.

**Daily Support for operations:**

• Monitor all systems associated with the SM building and maintain KPI’s to assure that they are operating properly and in compliance with internal and external requirements.
• Act as the single point of contact for the SM building to ensure compliance related activities such as deviations, change controls and CAPA’s are resolved and implemented in conjunction with Operations, Process Engineering, Supply Chain, HSE and Quality Assurance.
• Collaborate within the FUME organization to implement efficient and effective maintenance and reliability techniques in alignment with global engineering standards.
• Apply “hands-on” problem solving skills in quickly and efficiently resolving equipment failures, troubleshooting, demonstrati